Amoxil/Amoxil Forte Dosage/Direction for Use

Adults and Children >40 kg: Standard Dose: 250 mg 3 times daily, increasing to 500 mg 3 times daily for more severe infections.
High Dosage Therapy (Maximum Recommended Oral Dosage 6 g Daily in Divided Doses): A dosage of 3 g twice daily is recommended in appropriate cases for the treatment of severe or recurrent purulent infection of the respiratory tract.
Short Course Therapy: Simple Acute Urinary Tract Infection: Two 3-g doses with 10-12 hrs between the doses. Dental Abscess: Two 3-g doses with 8 hrs between the doses. Gonorrhea: 3 g as a single dose.
Helicobacter Pylori Eradication in Peptic (Duodenal and Gastric) Ulcer Disease: 750 mg-1 g twice daily in combination with a proton-pump inhibitor (eg, omeprazole, lansoprazole) and another antibiotic (eg, clarithromycin, metronidazole) for 7 days.
Children <40 kg: Standard Dose: 125 mg 3 times daily, increasing to 250 mg 3 times daily for more severe infections. Amoxil drops is recommended for children <6 months.
Acute Otitis Media: 750 mg twice daily for 2 days may be used as an alternative course of treatment.
Renal Impairment: In renal impairment, the excretion of the antibiotic will be delayed and depending on the degree of impairment, it may be necessary to reduce the total daily dosage according to the following scheme: Adults and Children >40 kg: Mild Impairment [creatinine clearance (CrCl >30 mL/min)]: No change in dosage. Moderate Impairment (CrCl 10-30 mL/min): 500 mg twice daily maximum. Severe Impairment (CrCl <10 mL/min): 500 mg/day maximum.
Children <40 kg: Mild Impairment (CrCl >30 mL/min): No change in dosage. Moderate Impairment (CrCl 10-30 mL/min): 15 mg/kg twice daily (500 mg twice daily maximum). Severe Impairment (CrCl <10 mL/min): 15 mg/kg once daily (500 mg maximum).
Patients Receiving Peritoneal Dialysis: 500 mg/day maximum. Dosing as for patients with severe renal impairment (CrCl <10 mL/min). Amoxicillin is not removed by peritoneal dialysis.
Patients Receiving Hemodialysis: Dosing as for patients with severe renal impairment (CrCl <10 mL/min).
Amoxicillin is removed from the circulation by hemodialysis. Therefore, 1 additional dose (500 mg for adults or 15 mg/kg for children <40 kg) may be administered during dialysis and at the end of each dialysis.
Prophylaxis of Endocarditis: See Table 2.

Click on icon to see table/diagram/image

Parenteral therapy is indicated if the oral route is considered impracticable or unsuitable, and particularly for the urgent treatment of severe infection.